KMS Institute of Vertebrate Paleontology and Paleoanthropology
| Genomic insights into the origin of farming in the ancient Near East | |
| Lazaridis, Iosif1,2; Nadel, Dani3; Rollefson, Gary4; Merrett, Deborah C.5; Rohland, Nadin1; Mallick, Swapan1,2,6; Fernandes, Daniel7,8; Novak, Mario7,9; Gamarra, Beatriz7; Sirak, Kendra7,10; Connell, Sarah7; Stewardson, Kristin1,6; Harney, Eadaoin1,6,11; Fu, Qiaomei1,12,13; Gonzalez-Fortes, Gloria14; Jones, Eppie R.15; Roodenberg, Songul Alpaslan16; Lengyel, Gyorgy; Bocquentin, Fanny18; Gasparian, Boris19; Monge, Janet M.20; Gregg, Michael20; Eshed, Vered21; Mizrahi, Ahuva-Sivan21; Meiklejohn, Christopher22; Gerritsen, Fokke23; Bejenaru, Luminita24; Blueher, Matthias25; Campbell, Archie26; Cavalleri, Gianpiero27; Comas, David28; Froguel, Philippe29,30; Gilbert, Edmund27; Kerr, Shona M.26; Kovacs, Peter31; Krause, Johannes32; McGettigan, Darren33; Merrigan, Michael34; Merriwether, D. Andrew35; O'Reilly, Seamus34; Richards, Martin B.36; Semino, Ornella37; Shamoon-Pour, Michel35; Stefanescu, Gheorghe38; Stumvoll, Michael25; Toenjes, Anke25; Torroni, Antonio37; Wilson, James F.39,40; Yengo, Loic29; Hovhannisyan, Nelli A.41; Patterson, Nick2; Pinhasi, Ron7; Reich, David1,2,6 | |
| 2016-08-25 | |
| 发表期刊 | NATURE
 |
| 卷号 | 536期号:7617页码:419-+ |
| 文章类型 | Article |
| 摘要 | We report genome-wide ancient DNA from 44 ancient Near Easterners ranging in time between similar to 12,000 and 1,400 BC, from Natufian hunter-gatherers to Bronze Age farmers. We show that the earliest populations of the Near East derived around half their ancestry from a 'Basal Eurasian' lineage that had little if any Neanderthal admixture and that separated from other non-African lineages before their separation from each other. The first farmers of the southern Levant (Israel and Jordan) and Zagros Mountains (Iran) were strongly genetically differentiated, and each descended from local huntergatherers. By the time of the Bronze Age, these two populations and Anatolian-related farmers had mixed with each other and with the hunter-gatherers of Europe to greatly reduce genetic differentiation. The impact of the Near Eastern farmers extended beyond the Near East: farmers related to those of Anatolia spread westward into Europe; farmers related to those of the Levant spread southward into East Africa; farmers related to those of Iran spread northward into the Eurasian steppe; and people related to both the early farmers of Iran and to the pastoralists of the Eurasian steppe spread eastward into South Asia. |
| WOS标题词 | Science & Technology |
| DOI | 10.1038/nature19310 |
| 关键词[WOS] | POPULATION HISTORY ; BRONZE-AGE ; SEQUENCE ; DNA ; NEANDERTHAL ; ANCESTRY ; EURASIANS ; EUROPEANS ; ADMIXTURE ; PLINK |
| 收录类别 | SCI ; AHCI |
| 语种 | 英语 |
| 项目资助者 | Irish Research Council(GOIPG/2013/36 ; Irish Research Council for Humanities and Social Sciences (IRCHSS) ERC Support Programme ; Bureau of International Cooperation of the Chinese Academy of Sciences ; National Natural Science Foundation of China(L1524016) ; Chinese Academy of Sciences(2015-DX-C-03) ; Chief Scientist Office of the Scottish Government Health Directorates(CZD/16/6) ; Scottish Funding Council(HR03006) ; Scottish Executive Health Department, Chief Scientist Office(CZB/4/285) ; German Research Foundation(CRC 1052 ; Wenner-Gren Foundation Dissertation Fieldwork grant(9005) ; National Science Foundation DDRIG(BCS-1455744) ; Federal Ministry of Education and Research, Germany(FKZ: 01EO1501) ; MRC 'QTL in Health and Disease' programme grant ; EC Commission, Directorate General XII (Supplementary Agreement ERBCIPDCT(940038 ; Leverhulme Trust's Doctoral Scholarship programme ; University of Pavia (MIGRAT-IN-G) ; Italian Ministry of Education, University and Research: Progetti Ricerca Interesse Nazionale ; National Geographic Society(8915-11) ; WennerGren Foundation(7481) ; Irene Levi-Sala CARE Foundation ; Israel Science Foundation(475/10) ; ERC(263441) ; NIH(GM100233) ; NSF HOMINID(BCS-1032255) ; GOIPD/2013/1) ; B01 ; 920032) ; B03 ; C01) |
| WOS研究方向 | Science & Technology - Other Topics |
| WOS类目 | Multidisciplinary Sciences |
| WOS记录号 | WOS:000382646600034 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://119.78.100.205/handle/311034/7029 |
| 专题 | 中科院古脊椎所（2000年以后） |
| 作者单位 | 1.Harvard Med Sch, Dept Genet, Boston, MA 02115 USA 2.Broad Inst MIT & Harvard, Cambridge, MA 02142 USA 3.Univ Haifa, Zinman Inst Archaeol, IL-3498838 Haifa, Israel 4.Whitman Coll, Dept Anthropol, Walla Walla, WA 99362 USA 5.Simon Fraser Univ, Dept Archaeol, Burnaby, BC V5A 1S6, Canada 6.Harvard Med Sch, Howard Hughes Med Inst, Boston, MA 02115 USA 7.Univ Coll Dublin, Sch Archaeol & Earth Inst, Dublin 4, Ireland 8.Univ Coimbra, Dept Life Sci, CIAS, P-3000456 Coimbra, Portugal 9.Inst Anthropol Res, Zagreb 10000, Croatia 10.Emory Univ, Dept Anthropol, Atlanta, GA 30322 USA 11.Harvard Univ, Dept Organism & Evolutionary Biol, Cambridge, MA 02138 USA 12.Max Planck Inst Evolutionary Anthropol, Dept Evolutionary Genet, D-04103 Leipzig, Germany 13.Chinese Acad Sci, IVPP, Key Lab Vertebrate Evolut & Human Origins, Beijing 100044, Peoples R China 14.Univ Ferrara, Dept Biol & Evolut, I-44121 Ferrara, Italy 15.Univ Cambridge, Dept Zool, Cambridge CB2 3EJ, England 16.JM van Nassaulaan 9, NL-2071 VA Santpoort Noord, Netherlands 17.Univ Miskolc, Dept Prehistory & Archaeol, H-3515 Miskolc, Hungary 18.French Natl Ctr Sci Res, UMR 7041, F-92023 Nanterre, France 19.Natl Acad Sci Republ Armenia, Inst Archaeol & Ethnol, Yerevan 0025, Armenia 20.Univ Penn, Museum Archaeol & Anthropol, Philadelphia, PA 19104 USA 21.Israel Antiqu Author, IL-91004 Jerusalem, Israel 22.Univ Winnipeg, Dept Anthropol, Winnipeg, MB R3B 2E9, Canada 23.Netherlands Inst Turkey, TR-34433 Istanbul, Turkey 24.Alexandru Ioan Cuza Univ, Fac Biol, Iasi 700505, Romania 25.Clin Endocrinol & Nephrol, Dept Internal Med & Dermatol, D-04103 Leipzig, Germany 26.Univ Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, Generat Scotland,Ctr Genom & Expt Med, Edinburgh EH4 2XU, Midlothian, Scotland 27.Royal Coll Surgeons Ireland, RCSI Mol & Cellular Therapeut, Dublin 2, Ireland 28.Univ Pompeu Fabra, Dept Ciencies Expt & Salut, Inst Biol Evolut CSIC UPF, Barcelona 08003, Spain 29.Univ Lille, CNRS, Inst Pasteur Lille, UMR EGID 8199, F-59000 Lille, France 30.Univ London Imperial Coll Sci Technol & Med, London Hammersmith Hosp, Dept Genom Common Dis, London W12 0HS, England 31.Univ Leipzig, Med Ctr, IFB Adipos Dis, D-04103 Leipzig, Germany 32.Max Planck Inst Sci Human Hist, D-07745 Jena, Germany 33.Univ Coll Dublin, Sch Hist, Newman Bldg, Dublin 4, Ireland 34.Geneal Soc Ireland, Dun Laoghaire, Dublin, Ireland 35.SUNY Binghamton, Dept Anthropol, Binghamton, NY 13902 USA 36.Univ Huddersfield, Sch Appl Sci, Dept Biol Sci, Huddersfield HD1 3DH, W Yorkshire, England 37.Univ Pavia, Dipartimento Biol & Biotecnol L Spallanzani, I-27100 Pavia, Italy 38.Inst Cercetari Biol, Iasi 700505, Romania 39.Univ Edinburgh, Usher Inst Populat Hlth Sci & Informat, Edinburgh EH8 9AG, Midlothian, Scotland 40.Univ Edinburgh, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Edinburgh EH4 2XU, Midlothian, Scotland 41.Yerevan State Univ, Ctr Excellence Appl Biosci, Yerevan 0025, Armenia |
| 推荐引用方式 GB/T 7714 | Lazaridis, Iosif,Nadel, Dani,Rollefson, Gary,et al. Genomic insights into the origin of farming in the ancient Near East[J]. NATURE,2016,536(7617):419-+. |
| APA | Lazaridis, Iosif.,Nadel, Dani.,Rollefson, Gary.,Merrett, Deborah C..,Rohland, Nadin.,...&Reich, David.(2016).Genomic insights into the origin of farming in the ancient Near East.NATURE,536(7617),419-+. |
| MLA | Lazaridis, Iosif,et al."Genomic insights into the origin of farming in the ancient Near East".NATURE 536.7617(2016):419-+. |
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